Does Protein Get Turned into Fat?

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Does Protein Get Turned into Fat? – Thomas DeLauer

Research study – JAMA

The function of this research study was to reveal the function of diet plan structure in action to overindulging and energy dissipation

More particularly, it took a look at whether the level of dietary protein impacted body structure, weight gain, and/or energy expense in topics randomized to among 3 hypercaloric diet plans: low protein (5%), regular protein (15%), or high protein (25%)

A single-blind, randomized regulated trial of 25 United States healthy, weight-stable male and female volunteers, aged 18 to 35 years with a body mass index in between 19 and 30.

The very first individual was confessed to the inpatient metabolic system in June 2005 and the last in October 2007.

After taking in a weight-stabilizing diet plan for 13 to 25 days, individuals were randomized to diet plans including 5% of energy from protein (low protein), 15% (regular protein), or 25% (high protein), which they were overfed throughout the last 8 weeks of their 10- to 12-week remain in the inpatient metabolic system.

Compared to energy consumption throughout the weight stabilization duration, the protein diets supplied around 40% more energy consumption, which represents 954 kcal/d (95% CI, 884–– 1022 kcal/d).


Overindulging produced substantially less weight gain in the low protein diet plan group (3.16 kg; 95% CI, 1.88–– 4.44 kg) compared to the typical protein diet plan group (6.05 kg; 95% CI, 4.84–– 7.26 kg) or the high protein diet plan group (6.51 kg; 95% CI, 5.23–– 7.79 kg) (P=.002).

Body fat increased likewise in all 3 protein diet plan groups and represented 50% to more than 90% of the excess saved calories.

Resting energy expense, overall energy expense, and body protein did not increase throughout overfeeding with the low protein diet plan. On the other hand, resting energy expense (regular protein diet plan: 160 kcal/d [95% CI, 102–– 218 kcal/d]; high protein diet plan: 227 kcal/d [95% CI, 165–– 289 kcal/d] and body protein (lean body mass) (typical protein diet plan: 2.87 kg [95% CI, 2.11–– 3.62 kg]; high protein diet plan: 3.18 kg [95% CI, 2.37–– 3.98 kg] increased substantially with the high and regular protein diet plans.

There are 2 kinds of amino acid carbon skeletons:

–– Glucogenic amino acids have a carbon skeleton that can be metabolically transformed to pyruvate or an intermediate of the citric acid cycle. These amino acids can be utilized to make glucose.

–– Ketogenic amino acids have a carbon skeleton that can be metabolically transformed to acetyl CoA or acetoacetyl CoA. They can not be transformed into glucose, however can be utilized to make ketone bodies and fats.



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